In Posthuman you play as one of the last human survivors in a world where nature is reclaiming the planet and our mutated offspring are working to eradicate us. Will you resist mutation and survive, or give in to the inevitable and join the mutants?

In the game, players start off as humans on a solitary journey to a rumored fortress harbouring a community of humans. To reach the fortress the players need to complete ten zones successfully. These zones are found on tiles of varying terrain that are drawn by the players as they explore the world. On their travels the players have the opportunity to meet other human players to trade items and use beneficial skills on each other. Will they strive to cling to their humanity and make a run for the fortress, thus winning the game? Or will they give in to the ever more tempting mutation, join the mutants, and deny the win from the rest of the humans?