Lupin The 3rd brings the characters of Kazuhiko Kato's classic manga series, Lupin III, to the game board, with players taking the role of one of five characters from the popular series (Lupin, Jigen, Goemon Ishikawa XIII, Fujiko Mine, and Inspector Zenigata).

In Lupin The 3rd, one player controls Inspector Zenigata along with his team of police agents, while the other players work secretly together to steal the treasure and escape. But, be wary of the mischievous Fujiko - he may betray the group and escape with the treasure, himself!